In this window you can specify the language of the Dr.Web Anti-virus GUI by selecting the necessary language in the Select language list.
The Notification types group box allows you to select the types of pop-up notifications which appear above the SpIDer Agent icon in the taskbar notification area. Components mentioned in this group box send notifications when a corresponding event happens (i.e. when a threat is detected or an update is performed).
For more details on the settings specified in this pane click the correspondent fragment of the window in the picture.